SH3 domains: modules of protein–protein interactions

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discovering domains mediating protein interactions

background: protein-protein interactions do not provide any direct information re­garding the domains within the proteins that mediate the interactions. the majority of proteins are multi domain proteins and the interaction between them is often defined by the pairs of their domains. most of the former studies focus only on interacting do­main pairs. however they do not consider the interaction...

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ژورنال

عنوان ژورنال: Biophysical Reviews

سال: 2012

ISSN: 1867-2450,1867-2469

DOI: 10.1007/s12551-012-0081-z